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Earlier items
- Rough Draft
of a Dog Genome
- Gene defect in Siberian huskies
& Samoyeds offers dog 'model' for studying inherited human blindness
- Population genetics:
more jobs than educated minds?
-
Human gene number climbs (full text: http://www.nature.com/nsu/010830/010830-4.html)
New estimate ups our gene number by a third.
24 August 2001
At around 30,000, the gene number estimated from the human genome
sequence seemed scant compared with the mustard weed's 25,000 and
the fruitfly's 13,000, as well as with previous, more generous estimates.
Even the public genome consortium and Celera's private effort managed
to agree roughly on this — albeit on the basis of different gene-prediction
programs. These estimates are too low, say Michael Cooke and colleagues
at the Genomics Institute of the Novartis Research Foundation in San
Diego, California. They compared the two gene sets and found that
they overlap only by about half1. The researchers detect the activity
of some of the genes in human tissues confirming that both groups
predicted real genes. If the rest of the mooted genes are genuine,
an estimate of 42,000 or more is closer
to the mark. "It says we don't know the complete set yet," says Cooke
— some genes may still have been missed by both groups.
see also: ns-gen-00-05-gene_number.html
- Assessing linkage disequilibrium
in a complex genetic system
- Mouse Gene Trap Helps Decipher
Brain's Wiring Diagram
- Humans
have genes for hundreds of olfactory receptors:
By comparing tiny variations in the DNA sequences of chimps and humans,
researchers in Israeli have concluded that changes in about 1,000
smell receptor genes contributed to the rise of the human race
- The
failure to clone more than six generations of mice hints at a hidden
defect in the animals
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